McGregor’s situation is a bit different than some other fighters on this list because it’s possible that he could lose his 155-pound title in 2018, but it may not come from a fight.
McGregor hasn’t competed inside the Octagon since winning the title at UFC 205 in November 2016.
He took on Floyd Mayweather this past August in a boxing match, and his fighting future is now uncertain. With that being said, it’s certainly a realistic possibility that McGregor could vacate his title or be stripped of it in 2018.
If he does elect to defend it, he won’t have an easy road either.
He’ll likely have to take on interim champion Tony Ferguson or top contender Khabib Nurmagomedov, two fighters who present incredibly difficult stylistic match-ups for McGregor.